Big Sam returns to face his former club in only his fourth match as Palace manager - and he will be looking to get a first win since taking charge of the Eagles at the back end of 2016.
One point from nine in Allardyce's first three games has seen Palace struggle to shake free from the difficult first half of the Premier League campaign they have endured. But, as with last season when the Eagles were suffering in the league, the Emirates FA Cup can offer a release from the toils of the top flight.
Saturday's opponents Bolton Wanderers are flying high in League One, sitting in second place, and are unbeaten in their last three games, beating Shrewsbury and Scunthorpe before drawing with Coventry last time out.
Phil Parkinson's side have beaten Grimsby Town and Sheffield United in their two FA Cup home draws so far this campaign, scoring four goals along the way. So they will be hoping to add a third victory to that list on Saturday.
Phil Parkinson: "This weekend's FA Cup game will be a good test for us. We will go into it as underdogs, but we're relishing the challenge.
"I have come across Sam Allardyce on numerous occasions throughout the years and he's a great guy.
"Palace have some real quality in their team and although they find themselves down at the bottom, they are a huge threat.
"Our players will be eager to show the football world what they are capable of against top flight opposition this weekend."
Crystal Palace: Loic Remy is in line to make his first appearance for Crystal Palace in this tie after he resumed full training last week.
Meanwhile, Wilfried Zaha will be unavailable as he is away at the Africa Cup of Nations but James McArthur and Scott Dann could be back after recent injuries.
Bolton Wanderers: Darren Pratley, Mark Howard and Mark Davies are all out for the Trotters.
Crystal Palace reached the FA Cup final last season; for the first time since 1989-90.
There have been just three goals scored in the last four competitive meetings between Bolton Wanderers and Crystal Palace.
Bolton have been eliminated in each of their last three FA Cup ties against Premier League opposition.
This is the fourth season in a row that Crystal Palace have been drawn away in the FA Cup third round, but the Eagles have won each of their last three ties.
Gary Madine has netted in all but one of his three FA Cup appearances for Bolton at the Macron Stadium (two goals).
Each of Crystal Palace's last seven goals in the FA Cup have been scored by different players (Wilfried Zaha, Martin Kelly, Yohan Cabaye, Fraizer Campbell, Connor Wickham, Yannick Bolasie and Jason Puncheon).
Referee: Roger East
Assistants: M McDonough & M Wilkes
Fourth Official: R Jones
Roger East has taken charge of 18 games in all competitions, including five Premier League games, handing out a total of 76 yellow and five red cards. He is yet to officiate a Palace or Bolton fixture this term.
LAST MEETING AT THE MACRON STADIUM
29th September 2012
Bolton Wanderers 0-1 Crystal Palace
A late Glenn Murray penalty settled this tie in favour of the Eagles, as they continued on their way to a 14-game unbeaten streak in English football's second tier.
Beating Bolton away was the fifth game in that early season run which saw Palace propel to the top of the table and - after a dramatic second half of the campaign, come May - win promotion via the play-offs.
Wilfried Zaha, a constant menace on the day, won a late penalty after drawing a foul from Zat Knight, which Glenn Murray converted for his sixth goal of the season - on his way to 30 league goals in 2012-13.
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