Former Palace stars Eddie McGoldrick and Simon Osborn will once again don the famous red and blue to help Eagles fans try and beat their Brighton counterparts.
On Friday April 19th supporters from both clubs will meet at the Dripping Pan stadium in Lewes for the 12th annual Robert Eaton Memorial Fund match.
Palace's famous Crystal Girls cheerleaders will also be there to cheer on the Eagles and perform a dance at half-time.
The Seagulls currently lead 7-4 in the series and Palace fans will be keen to claw back a result - with the help of Osborn and McGoldrick who notched up 261 games for the Eagles between them.
The REMF fund was set up after Brighton fan Robert Eaton was killed in the 9/11 attacks in New York City in 2001 and has since raised more than £100,000 for disadvantaged children in America, Sussex, Croydon and Africa.
The games are fiercely contested with plenty of tasty challenges. Just ask former Albion star Peter Ward who was kicked all over the park during his first involvement in the annual game in 2009. He will be turning out for the Seagulls this year again.
To see if McGoldrick and Osborn can help the Palace fans to a victory this year come down to the Dripping Pan in Lewes on Friday. Kick-off is 7.45pm and entry is £5 with U16s getting in free.
For more information or to donate to the fund visit remf.org.uk