Palace's academy side slipped to their third defeat in their last four outings after Charlton snatched a winner five minutes from time to pip their south London rivals at Beckenham.
Academy boss Ken Gillard continued to blood youngsters from the under-16s side, and after Sam Woods and Kian Flanagan got their debuts at this level in the goalless draw against Brentford the previous week, centre-forward Victor Fundi was handed a start this time round.
He impressed in his first outing in a Palace shirt, despite a poor surface which restricted the amount of chances. The visitors enjoyed the better of the opening 20 minutes but couldn't break down a strong Eagles backline, and later Michael Phillips saw a good one-on-one chance go begging after being played in by Andre Coker.
Coker was at it again after the interval when he tucked in Corie Andrews who went on-on-one with the Addicks goalkeeper but a heavy touch saw him take the ball away from goal and from a tight angle he could only hit it straight at the custodian.
Palace almost gifted their neighbours a goal when Oliver O'Dwyer was robbed by a Charlton attacker who raced towards goal with a teammate in support, but Ben Wynter got back to make an excellent saving tackle and keep the scores level.
The Eagles were forced to name trialist keeper Joe Tupper in their side, who was standing in for the injured Oliver Pain, and he made two great saves during the second 45, firstly tipping a piledriver of a shot from range over the bar before springing to his left to deflect another effort from the edge of the box to safety.
Late on in the game another debutant was handed a chance when Levi Lumeka came on for his under-18s bow, but five minutes from time the away side got their noses in front.
A corner into the box was fumbled by Tupper and a Charlton player managed to slide in and bundle to ball into the net and grab the win and dent Gillard's side's hopes of reaching the end of the season play-offs.