Palace were hoping to bounce back from last weekend's narrow home defeat to Premier League leaders Manchester City, by getting back to winning ways away from Selhurst Park at Tottenham Hotspur, but it wasn't to be.
It was the home side who started the clash on the front foot at White Hart Lane, with Spurs enjoying spells with the ball, which Palace dealt with calmly and competently. The opening 20 minutes saw Tottenham looking the sharper, more dangerous side, but they struggled to find a way through the Eagles' defence.
The visitors' two best chances of the opening quarter of the game came in quick succession. Firstly, a low, powerful Sako cross was turned behind for a corner and from the resulting set piece Hangeland had a half-volley saved by Hugo Lloris.
It signalled the start of Palace edging themselves into the game, with Bolasie fashioning a chance for himself moments later.
Spurs continued to press though, and soon found themselves creating chances again. Alex McCarthy did well to parry a Dele Alli shot too wide for Harry Kane to shoot on the follow up. The striker hit a low cross back into a dangerous area, but Spurs had no one there to meet it.
Bolasie began to grow into the game for Palace, creating a few more chances for himself as the first half drew to a close. A free kick, won by the winger, was taken by Sako and his powerful effort nearly had the beating of Lloris.
Yohan Cabaye was inches away from breaking the deadlock, when his venomous strike cannoned back off the post and away from any Palace attackers. It was the last real chance of the half, with the two sides going in to the break level at 0-0.
The introduction of Fraizer Campbell at half time gave Palace a recognised striker to aim for up top, but the Eagles still found themselves dealing with a lot of pressure from the home side. McCarthy did well to save a Lamela free kick and the defence calmly cleared a succession of corners, but Palace were having to weather the storm a bit.
Left-back Ben Davies looked to have nodded Spurs ahead on 57 minutes, but he was deemed to have been offside, following a flurry of chances for the home side.
Sako nearly put Palace ahead, but Hugo Lloris pulled off a fantastic one-handed save to tip his effort onto the post and away. Both sides were pushing for the opener and the later it got, the more it felt as though the game would be decided by one.
Finally, the game had a goal. Heung-min Son was played through by substitute Christian Eriksen and he fired low beyond McCarthy following a quick counter-attack by Spurs.
Palace tried to find a way back into the game, but Spurs looked deadly on the break, with Alli nearly doubling their advantage on the counter. Despite some late pressure from the visitors, Son's strike was enough to settle it in Spurs' favour.
Palace XI: McCarthy; Kelly, Hangeland, Delaney (C), Souare; McArthur (Mutch, 75), Cabaye; Zaha (Campbell, 45), Puncheon, Sako (Bamford, 83); Bolasie.
Subs: Hennessey, Mariappa, Ledley, Lee.
Spurs XI: LLoris (C); Walker, Alderweireld, Vertonghen, Davies; Dier, Alli; Lamela (Carroll, 86), Chadli (Eriksen, 65), Son (Clinton, 78); Kane.
Subs: Vorm, Tripper, Fazio, Clinton, Townsend.