Wayne Hennessey and Joe Ledley were left frustrated after Georgia held Wales to a 1-1 2018 World Cup qualifying draw in Cardiff on Sunday night.
The Palace pair once again started the game for Chris Coleman's men, just as they had done on Thursday evening in their 2-2 draw in Austria, and things looked to be going as expected when Gareth Bale headed in a Ledley corner after 10 minutes.
But having struggled to find a second goal to kill off the game, Wales were pegged back on 57th minutes when Tornike Okriashvili ghosted in unmarked to head past a helpless Hennessey and get the minnows level.
From that point Wales were indebted to their goalkeeper, as after Ledley left the fray after a 73 minute stint, Hennessey was forced into a couple of good stops and denied Levan Mchedlidze when he was one-on-one.
The draw proved costly as Wales slipped to third in their group after wins for Serbia and the Republic of Ireland saw them leapfrog them, with Serbia next up in November for Coleman's side.
Elsewhere on international duty, Christian Benteke came on in the 82nd minute with Belgium cruising to a 4-0 win against Bosnia and Herzegovina in Brussels, who should also run up a number of goals against Gibraltar in Faro on Monday night.
There was also an emphatic 4-1 win for France as they drubbed Bulgaria in Paris, but Yohan Cabaye and Steve Mandanda failed to add to their international cap haul ahead of a tasty meeting with Holland in Amsterdam also on Monday.
Meanwhile, injury has forced Bakary Sako to withdraw from the Mali squad, who lost 3-1 to the Ivory Coast in their first qualifier over the weekend.
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