Roy Hodgson has made two changes to the Palace side this evening with Jeffrey Schlupp and Martin Kelly returning to the starting eleven.
Timothy Fosu-Mensah is ineligible to play against his parent club United so Kelly comes back into the back four for the first time in a month, and Schlupp returns after nearly two months, at the expense of Jairo Riedewald. James Tomkins has shaken off the cramp he suffered against Spurs.
Palace's latest signing Diego Cavalieri makes the bench as replacement goalkeeper, as does Polish centre-back Jaroslaw Jach - making the matchday squad for the first time after joining the Eagles in January.
Palace: Hennessey, Van Aanholt, Milivojevic (c), Tomkins, Sørloth, Townsend, Schlupp, Benteke, McArthur, Wan-Bissaka, Kelly.
Subs: Cavalieri, Lee, Souare, Delaney, Rakip, Jach, Riedewald.
Manchester United: De Gea, Lindelof, Pogba, Sanchez, Lukaku, Smalling, Lingard, Young, Valencia (c), Matic, McTominay.
Subs: Pereira, Bailly, Mata, Carrick, Rashford, Shaw, Darmian.