Roy Hodgson has made just one change to the team he fielded on Saturday in Crystal Palace's 4-1 victory over Leicester City, bringing in Martin Kelly for the injured Mamadou Sakho.
Kelly has enjoyed a fine run of form lately for the Eagles and extended his contract with the club recently.
Wilfried Zaha again joins Michy Batshuayi, with the pair netting three goals between them on Saturday.
United have made a trio of changes to the side which lined-up against Liverpool on Sunday, with Alexis Sanchez, Fred and Diogo Dalot coming in for Ander Herrera, Juan Mata and Marcus Rashford. Rashford makes the bench but the other two are unavailable through injury.
19-year-old Tahith Chong also makes the bench along with 17-year-old James Garner.
Palace: Guaita, Van Aanholt, Tomkins, Kelly, Ward, Schlupp, Milivojevic, McArthur, Zaha, Batshuayi, Townsend.
Subs: Hennessey, Dann, Riedewald, Kouyate, Meyer, Ayew, Benteke.
United: De Gea, Shaw, Lindelof, Smalling, Young, Dalot, Pogba, McTominay, Fred, Sanchez, Lukaku.
Subs: Romero, Bailly, Rashford, Pereira, Rojo, Garner, Chong.