The fixture will take place at Old Trafford on Tuesday, 26th September, kicking off at 20:00 BST. It will be shown live in the UK on Sky Sports.
The match marks Palace’s first against Manchester United in the League Cup since a famous fifth-round victory at Old Trafford in November 2011.
On that occasion, a Darren Ambrose wondergoal and a Glenn Murray header saw the Eagles – then in the Championship – eliminate their hosts after extra time.
This season, should the initial 90 minutes end in a draw, the match will go straight to penalty kicks, with extra-time not used until the semi-finals.
Ticketing details will be released across cpfc.co.uk, the official Palace app and our social media channels in due course.
Manchester United v Palace
- Tuesday, 26th September
- 20:00 BST
- Old Trafford
- Live on Sky Sports