After a sterling show against Burnley on Saturday that brought a first league success in eight, Palace go looking for their first consecutive Premier League wins of the campaign at the home of their arch-rivals, and Hodgson has rewarded all those players that beat the Clarets and got a goalless draw at Old Trafford with another start.
It also means that Wilfried Zaha will make his 300th appearance for the Eagles against the side that he has scored five goals against in that time - more than any other opponent.
Brighton meanwhile have made two changes to their side that came from behind to beat Huddersfield Town on Saturday, with Glenn Muray returning to the starting line-up after being rested for the game against the Terriers and goalscorer Florin Andone dropping to the bench.
The other switch sees long-serving Bruno drop out of the squad entirely, with his spot at right-back being taken by Martin Montoya.
Brighton: Ryan, Montoya, Duffy, Dunk, Bernado, Gross, Propper, Bissouma, March, Murray, Izquierdo. Subs: Steele, Bong, Balogan, Kayal, Knockaert, Locadia, Andone.
Palace: Hennessey, Wan-Bissaka, Tomkins, Sakho, Van Aanholt, McArthur, Kouyaté, Milivojevic, Meyer, Townsend, Zaha. Subs: Guaita, Ward, Kelly, Schlupp, Puncheon, Sørloth, Ayew.