Palace will welcome Middlesbrough to Selhurst Park on Tuesday, 8th September, kicking-off at 19:45 BST.
If our third-round tie is level after 90 minutes, it will go straight to penalties to decide who advances; extra-time is only used in the Carabao Cup from the semi-finals onwards.
Palace have fallen away to Arsenal at the quarter-final stage of the competition in both of the last two seasons.
The tie will be broadcast live on Sky Sports in the UK, as with all ties from the competition this season.
For overseas supporters, selected matches will be made available via the EFL's international broadcast partners.
Ticketing information will be announced in due course.