Find out everything you need to know about the next stage of the competition below...
The draw
With third-round ties split across two weeks due to European scheduling, Palace will have to wait until next Wednesday, 16th September to find out their opposition in the last 16.
The fourth-round draw will take place live on Sky Sports following the conclusion of the televised tie between Manchester United and Brighton & Hove Albion that night.
With that match set to kick off at 20:00 BST, should penalties be avoided, it is likely the draw will begin at around 22:15.
The fixtures
Fourth-round matches are due to be played in the week commencing Monday, 26th October.
Once again, any matches which end in a draw in the fourth-round will go straight to penalties. Extra-time is only used in the Carabao Cup from the semi-finals onwards.
Who else is in the draw?
Unlike in the third-round, there will be no draw conditions required, meaning any team can draw any other team still in the competition.
Some 10 ties are still to be played next week (week commencing Monday 14th September).
However, Palace will definitely be joined in the fourth round by fellow Premier League sides Bournemouth, Sunderland and Newcastle, as well as League One side Bradford City.
The likes of Chelsea, Liverpool, Tottenham, Arsenal, Manchester United, Aston Villa and Manchester City are all still to play next week.
Get news of the fourth-round draw delivered straight to your phone within minutes of it happening, by downloading the Official Crystal Palace App.