From the side that started the Conference League quarter-final second leg against Fiorentina last Thursday, Will Hughes and Jefferson Lerma come into the midfield, replacing Daichi Kamada and Adam Wharton.
The other switches see Brennan Johnson come into the attack, joining Yéremy Pino and Jørgen Strand Larsen who replaces Jean-Philippe Mateta.
Mateta and Ismaïla Sarr will be available from the bench, as they were in our last home Premier League game, a 2-1 win over Newcastle.
The substitutes bench available also includes Kamada and Justin Devenny, as well as Nathaniel Clyne and Chadi Riad.
Dean Henderson is selected in goal to captain the side, while Maxence Lacroix is fit to play after overcoming the injury that saw him withdrawn in Florence.
Ahead of the visit from the Hammers, Glasner was asked about his striking options by Sky Sports, saying: “Both Jørgen [Strand Larsen] and JP [Mateta] know that we need both of them, and it's really easy because they are both such great guys.
"And I think the Newcastle game was great evidence of this. Jørgen really played well, he worked very hard in the first 60 minutes and then JP came on and helped us to win the game.
"Jørgen did the same when he arrived, first again Brighton and then when he scored two great goals against Burnley.
"When you have so many games to play, you need two strikers, particularly with Eddie Nketiah having a frustrating season with injury. So it's good we have two strikers.
West Ham, perhaps unsurprisingly, name an unchanged team after they defeated Wolves 4-0 in their last outing ten days ago.
The Hammers go into tonight’s game one place and one point ahead of Tottenham in 18th, and one place and four points behind 16th-place Forest.
Palace: Henderson (GK), Richards, Lacroix, Canvot, Muñoz, Hughes, Lerma, Mitchell, Johnson, Pino, Strand Larsen.
Subs: Benítez (GK), Clyne, Riad, Sosa, Cardines, Devenny, Kamada, Sarr, Mateta.
West Ham: Hermansen (GK), Walker-Peters, Mavropanos, Disasi, Diouf, Fernandes, Souček, Bowen, Summerville, Pablo, Taty.
Subs: Areola (GK), Wan-Bissaka, Scarles, Todibo, Potts, Magassa, Kanté, Adama, Wilson.
Match Details
Crystal Palace v West Ham United
- Monday, 20th April
- 20:00 BST
- Selhurst Park
- Live audio commentary on Palace TV+