New goalkeeper Stephen Henderson starts in goal having made his first Palace appearance at Barnet. Sakho will play alongside Sam Woods, with Nikola Tavares and new U23s addition Lewis Hobbs as full-backs. Jairo Riedewald joins Luke Dreher and Giovanni McGregor in the centre of midfield, with Brandon Pierrick, Wickham and James Daly likely to feature as a front three.
A notable inclusion in the hosts' starting XI is former Eagle Kwesi Appiah, and is acting as AFC Wimbledon's captain tonight.
Gold, Junior Gold and International members who purchased a membership before 19:00 BST on Monday 29 July can watch the game exclusively live on the official Palace app and eagles.cpfc.co.uk. Non-members can stay up to date with live Twitter commentary @cpfc, and enjoy free highlights and post-match reaction later tonight on Palace TV.
AFC Wimbledon: Tzanev (GK), Stabana, Osew, Procter, McDonald, Macnab, McLoughlin, Rudoni, Pinnock, Appiah (c), Connolly.
Subs: Trott (GK), Kalambayi, Collins, Hartigan, Kaja, Wood.
Crystal Palace: Henderson (GK), Tavares, Hobbs, Sakho, Woods, Riedewald, Dreher, McGregor, Daly, Wickham, Pierrick.
Subs: Tupper (GK), Inniss, D Boateng, M Boateng, Flanagan, Lokilo.