The German will make his second Eagles start in the Premier League this season, replacing Jordan Ayew in the only change from the 2-2 draw against Arsenal seven days ago. The Ghanaian is included on the bench.
The Blues meanwhile are unchanged from their 4-0 thrashing of Burnley last weekend, meaning that Eden Hazard starts once again on the bench. Also listed as a substitute is ex-Eagle Ruben Loftus-Cheek as he hopes to face his former side.
Chelsea: Arrizabalaga, Azpilicueta, Rudiger, Luis, Alonso, Kante, Jorginho, Barkley, Pedro, Morata, Willian. Subs: Caballero, Zappacosta, Cahill, Fabregas, Kovacic, Loftus-Cheek, Hazard.
Palace: Hennessey, Wan-Bissaka, Sakho, Tomkins, Van Aanholt, McArthur, Kouyate, Milivojevic, Meyer, Townsend, Zaha. Subs: Guaita, Kelly, Schlupp, Riedewald, Puncheon, Ayew, Sørloth.