James Tomkins and Yohan Cabaye both miss out and Scott Dann, who was on the bench at Brighton, is also ruled out with illness.
Martin Kelly and James McArthur also return to the starting eleven.
A further change was needed as Wayne Hennessey was injured in the warm up and is replaced by Julian Speroni.
Alan Pardew has named his first line-up as West Brom boss and has made one change from midweek with Jay Rodriguez coming into the Baggies side.
West Bromwich Albion: Foster, Nyom, Gibbs, Robson-Kanu, Evans, Livermore, Rondón, Barry, Rodriguez, Hegazi, Field.
Subs: Myhill, Yacob, McClean, Burke, Krychowiak, McAuley, Melbourne.
Crystal Palace: Speroni, Ward, Milivojevic, Loftus-Cheek, Townsend, Zaha, Sakho, Schlupp, Benteke, McArthur, Kelly.
Subs: Van Aanholt, Fosu-Mensah, Sako, Puncheon, Riedewald.