The match cannot be shown on television due to competition regulations, but if you can't make it to Devon, there are still plenty of ways you can follow all the action LIVE...
- Manager: Steven Schumacher
- Last season: 1st (EFL League One)
- Nickname: The Pilgrims
- Ground: Home Park
- Founded: 1886 (137 years ago)
What's the story?
It's perhaps not quite the same distance as Plymouth to Massachusetts – the journey undertaken by the Pilgrims to reach the New World in 1620.
But while a lengthy enough trip from south London to south-west Devon awaits Crystal Palace on Tuesday, they come up against a club on quite the remarkable (metaphorical) voyage in recent seasons.
The Championship is as high as Plymouth Argyle have ever climbed in the post-War era. They have struggled to remain there: a run of eight seasons between 2002 and 2010 culminated in back-to-back relegations and a six-season spell in EFL League Two.
Yet Argyle's last four years have seen greener days return once more to Devon, promotion via points-per-game in the curtailed 2019/20 campaign under Ryan Lowe setting up a relatively rapid rise in League One.
The departure of Lowe to Preston North End in early December 2021 was no doubt a blow to the Green Army, but under his replacement Steven Schumacher – Lowe's assistant during that rise – their good form has continued, fuelled by the goals of Rangers academy product Ryan Hardie.
Inconsistencies in 2021/22 were addressed last season as Argyle dominated a talented League One line-up to win the competition outright, an eye-catching 31 victories helping the Green Army to pick up 101 points and pip the likes of Ipswich Town and Sheffield Wednesday to the title.
This talented Plymouth team have began their latest Championship campaign with a win, a draw and two defeats – both in unfortunate circumstances in the final seconds of injury time – thus far.
Can the Pilgrims' latest second-tier venture stay afloat? Time will tell – but an excursion into the latter stages of the Carabao Cup would also be welcomed.